What is it? omeprazole (losec ®) is a medicine called a proton pump inhibitor (ppi)ppis reduce the production of stomach acid ppis are used to treat indigestion, gastro-oesophageal reflux and stomach ulcers, all of which are more common in pregnancy as a result of the normal changes that occur as pregnancy progresses. Omeprazole in early pregnancy. Although omeprazole (prilosec) is the most commonly used such drug in the us, evidence of its safety in pregnancy is limited this swedish study compared the risk of birth defects in 282 women who reported omeprazole use in early pregnancy with that in about 200,000 babies born to all swedish women from 1995 to early 1997.
omeprazole in early pregnancy
Kallen b delivery outcome after the use of acid-suppressing drugs in early pregnancy with special reference to omeprazole br j obstet gynaecol 1998 ;105: 877 - 881 crossref. Because prilosec has a category c rating, doctors typically recommend alternative medications for pregnant women.safe alternatives for treating pregnancy heartburn including over-the-counter tums. The safety of fetal exposure to proton-pump inhibitors during pregnancy. dig dis sci 57:699-705. nikfar s, et al. 2002. use of proton pump inhibitors during pregnancy and rates of major malformations: a meta-analysis. dig dis sci 47:1526-9. pasternak b, hviid a. 2010. use of proton-pump inhibitors in early pregnancy and the risk of birth defects..