Dexilant (dexlansoprazole) is a medication used to treat acid reflux (also called gerd) or heartburndexilant may also be used to heal erosive esophagitis and to maintain the healing of erosive esophagitis dexilant is part of a class of medications called proton pump inhibitors (ppi's). Acid reflux medicine dexilant. Medication for acid reflux dexilant common heartburn triggers (