To test the effect of changing bile acid composition of the refluxed material on the symptoms and gastric mucosal histology, 12 patients with symptomatic alkaline reflux gastritis were treated for 1 mo with placebo and for 1 mo with ursodeoxycholic acid, 1000 mg/day. Ursodeoxycholic acid treatment of bile reflux gastritis. Lifestyle adjustments and medications can be very effective for acid reflux into the esophagus, but bile reflux is harder to treat there is little evidence assessing the effectiveness of bile reflux treatments, in part because of the difficulty of establishing bile reflux as the cause of symptoms medications ursodeoxycholic acid.
ursodeoxycholic acid treatment of bile reflux gastritis