Q i just took a ppi heartburn pill for my acid reflux, but i’m still in a lot of discomfort can i take an antacid tablet or a medicated effervescent drink while i’m waiting for the ppi to kick in? a in most cases, it’s perfectly safe to use a fast-acting antacid in combination with an h2ra or ppi. Acid reflux fast acting heartburn relief. The oldest and best-known medicines for treating heartburn, they have remained popular because they’re fast-acting, inexpensive, available without a prescription, and are safe for most people.
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